Metodine

Metodine (Di-iodohydroxyquinoline and Metronidazole) by Searle is a 60ml (Approx) Suspension. It is used to treat certain intestinal infections caused by parasites.

Package Contains: Each Metodine package contains a Suspension (syrup) bottle of 60ml & a leaflet.

Composition: Each 5 ml contains:

Di-iodohydroxyquinoline U.S.P. 200mg

Metronidazole Benzoate equivalent to Metronidazole B.P. 200mg

Dosage & Administration: To be sold on prescription of a registered medical practitioner only

For Children: Upto 4 years: 1 teaspoonful (5ml) thrice daily for 5-10 days.

4-12 years: 2 teaspoonfuls (10ml) thrice daily for 5-10 days or as directed by the physician.

Uses/ Indications: Metronidazole Suspension is indicated for the treatment of intestinal and extra-intestinal amoebiasis, amoebic liver abscess, and in the treatment of giardiasis.

Side Effects/ Adverse Reactions: Di-iodohydroxyquinoline: The following side/adverse effects have been selected on the basis of their potential clinical significance (possible signs and symptoms in parentheses where appropriate)-not necessarily inclusive:

Those indicating need for medical attention: Incidence is less frequent

Fever or chills.
Hypersensitivity (skin rash, hives, or itching).
Thyroid gland enlargement (swelling of the neck).

With prolonged, high doses of 8-hydroxyquinolines, Children may be more susceptible.

Optic atrophy (blurred vision or any change in vision).
Optic neuritis (decreased vision or eye pain).
Peripheral neuropathy (numbness, tingling, pain, or weakness in hands or feet).
Subacute myelo-optic neuropathy (blurred vision or any change in vision, clumsiness or unsteadiness, increased weakness, or muscle pain).

Those indicating need for medical attention only if they continue or are bothersome:

Incidence more frequent: Gastrointestinal disturbances (diarrhea, nausea or vomiting; stomach pain).
Incidence is less frequent: Headache. Itching of the rectal area.

Before using this medication, Conditions affecting use, especially:

Hypersensitivity to di-iodohydroxyquinoline, cloroxine, iodine, pamaquine, pentaquine, primaquine, or other 8-hydroxyquinolines.
Use in children: Children may be more likely to develop side effects such as optic atrophy, optic neuritis, and peripheral neuropathy, especially with long-term, high-dose therapy.
Other medical problems, especially hepatic or renal disease.

Contraindications: Hypersensitivity to 8-hydroxyquinoline, iodine-containing preparations, metronidazole or other nitroimidazole derivatives; hepatic damage; active organic disease of the CNS; patients with a history of blood dyscrasia; and pre-existing optic neuropathy. Because metronidazole crosses the placental barrier, Metodine is contraindicated during the first three months of pregnancy.

Instruction: Use as directed by the physician. Shake well before use. Protect from moisture, freezing, excessive heat and sunlight. Keep out of the reach of children.

Manufacturer & Buy Online:

Metodine suspension is manufactured by: The Searle Company Limited.

This is the link to the manufacturer: https://searlecompany.com/

You can buy it online at: https://www.dvago.pk

It is available online, or you can buy it from any nearby pharmacy. It is currently (2026) available at the retail price of around 200 rupees.

By: Urooj