Maxima Suspension

Maxima Suspension (CEFIXIME) by Macter, butterscotch candy flavour 100mg/5ml strength granule powder for oral suspension. It becomes 30 ml suspension (when reconstituted). It is a third-generation oral cephalosporin antibiotic.

Package Contains: Each Maxima package contains a 30ml suspension bottle, when reconstituted, in a strength of 100mg/5ml, a measuring spoon & a leaflet. It is also available as 200mg/5ml suspension, 400mg capsules, and 200mg tablets.

Composition: When reconstituted as directed,

Each 5 ml contains:

Cefixime trihydrate USP equivalent to

Cefixime 100 mg

USP Specifications.

Method of reconstitution: For preparation of suspension, add cool boiled water upto the mark on the label & shake well to form a uniform suspension. For accurate measurement of dosage, a spoon is provided.

Dosage: As directed by the physician.

Uses/ Indications: Maxima Suspension is an orally active cephalosporin antibiotic, which has marked in vitro bactericidal activity against a wide variety of Gram-positive & Gram-negative organisms. It is indicated for the treatment of the following acute infections when caused by susceptible microorganisms.

Upper respiratory tract infections (URTI): eg. otitis media, sinusitis, pharyngitis & tonsillitis.
Lower respiratory tract infections (LRTI): e.g. bronchitis.
Urinary tract infections (UTI): e.g. cystitis, cystourethritis, uncomplicated, pyelonephritis.
Uncomplicated gonorrhoea: (cervical/urethral, rectal and pharyngeal).
In vitro activity: Clinical efficacy has been demonstrated in infections caused by commonly occurring pathogens including Streptococcus pneumoniae, Streptococcus pyogenes, Escherichia coli, Proteus mirabilis, Klebsiella species, (beta-lactamase positive & negative) & Enterobacter species. Maxima is highly stable in the presence of beta lactamase enzymes.
Maxima have been shown to be active in vitro against most strains of the following organisms: however, clinical efficacy has not been established. Streptococcus agalactiae, Haemophilus parainfluenzae (beta-lactamase positive & negative strains), Proteus vulgaris, Pasteurella multocida (P. septica), Providencia species, Salmonella species, Shigella species, Citrobacter diversus & Serratia marcescens.
Most strains of Enterococci (Streptococcus faecalis, group D streptococci) & Staphylococcus (including coagulase positive & negative strains & methicillin-resistant strains) are resistant to Maxima. In addition, most strains of Pseudomonas, Bacteroides fragilis, Listeria monocytogenes & Clostridia are resistant to Maxima.

Side Effects: Maxima Suspension is generally well tolerated. The majority of adverse reactions observed in clinical trials were mild and self-limiting in nature.

Gastrointestinal Disturbances: The most frequent side effects seen with Maxima are diarrhoea and stool changes. Some cases of moderate to severe diarrhoea have been reported; this has occasionally warranted cessation of therapy. Maxima should be discontinued if marked diarrhoea occurs. Other Maxima gastrointestinal side effects seen less frequently are nausea, abdominal pain, dyspepsia, vomiting and flatulence. Pseudomembranous colitis has been reported (see above).
Central Nervous System: Headache and dizziness.
Hypersensitivity Reactions: Allergies in the form of rash, pruritis, urticaria, drug fever and arthralgia have been observed. These reactions usually subsided upon discontinuation of therapy.
Hematological and Clinical Chemistry: Thrombocytopenia, leukopenia and eosinophilia have been reported. These reactions were infrequent and reversible. Mild transient changes in liver and renal function tests have been observed.
Miscellaneous: Other possible reactions include genital pruritis and vaginitis.

Contraindications: Patients with known hypersensitivity to cephalosporin antibiotics.

Instruction:

Store between 15°C to 30°C.
Protect from sunlight, heat and moisture.
Keep out of the reach of children.
Shake well before use.
Close the bottle properly after use.
The reconstituted suspension should be kept at 8°C to 15°C, so that the potency of the product remains stable and can be used within 7 days.
To be sold on the prescription of a registered medical practitioner only.
For detailed information, see the direction circular inside.

Manufacturer & Buy Online:

Maxima Suspension is manufactured by: Macter International Limited.

This is the link to the manufacturer: https://macter

You can buy it online at: https://chemistdirect

It is available online, or you can buy it from any nearby pharmacy. It is currently (2026) available at the retail price of around 270 rupees.

By: Urooj