ENFLOR

Enflor sachet 250 (Saccharomyces boulardii) (lyophilized for oral use) 10 powder sachets for oral use in sachet. It is anti-diarrheal. Saccharomyces boulardii is a non-pathogenic live yeast that has been successfully used for years in the prevention and treatment of diarrhoea of various origins.

Package contains: The box of Enflor contains 10 sachets of 250mg each. It is also available in capsules.

Composition:

Each sachet contains: Saccharomyces boulardii CNCM I-7545 250mg (Lyophilized).

Excipients: Lactose monohydrate, fructose, tutti frutti aroma (containing sorbitol: E420), anhydrous colloidal silica.

The product complies with Hilton Pharma specs.

Dosage: Take 1 to 2 sachets twice daily or as directed by the physician. For further information please see package insert.

Direction for use: The powder of the sachet must be stirred into a glass of water, beverages or semi liquid food and take it immediately. Do not mix Enflor into very hot or very cold drinks or foods.

Due to a risk of airborne contamination, sachets should not be opened in patient rooms. Healthcare providers should wear gloves during handling of probiotics for administration, then promptly discard the gloves and properly wash their hands.

Therapeutic Indications:

Enflor is indicated for the prevention and treatment of diarrhoea of different aetiologies in adults and children, such as:
Acute infectious (viral or bacterial) diarrhoea in conjugation with oral rehydration.
Antibiotic-Associated Diarrhoea (AAD) and treatment and prevention of digestive complication of antibiotic therapy: diarrhoea, colitis.
Recurrence of Clostridium difficile Disease (CDD) in addition to vancomycin /metronidazole, etc.

Pharmacodynamics: Saccharomyces boulardii is an intestinal replacement flora, which acts as an antidiarrhoeal microorganism in the digestive tract. It is:

Anti-inflammatory.
Anti-microbial.
Enzymatic.
Metabolic.
Anti-toxinic.
Immuno-enhancing activities which are beneficial when Saccharomyces boulardii is used to treat diarrhoea of various origins (infectious, i.e. viral/bacterial, or non-infectious) in humans.

Contraindications: Known hypersensitivity to one of the components; allergy to yeast, especially Saccharomyces boulardii, patients having a central venous catheter; critically ill patients or immunocompromised patients due to risk of fungemia.

Drug Interactions: Due to the fungicidal nature of Saccharomyces boulardii, it must not be administered at the same time as oral or systemic antifungal treatment.

Warnings & Precautions: You should not take this medicine if you have lactose intolerance.

The sachet contains 471.90mg fructose in each sachet. In case of frequent use or over a long period of time (e.g. for two weeks or longer), fructose can damage teeth.

Patients with hereditary fructose intolerance (HFI), a rare genetic disorder in which a person cannot break down fructose, should not take/be given this medicinal product.

Condition & Population Related: Diarrhoea might be one of the symptoms of more dramatic underlying diseases. In adults and in children over 6 years of age, if diarrhoea persists after 2 days or if blood in faeces appears or if fever appears, treatment should be reconsidered and the necessity to introduce oral or parenteral rehydration should be considered.

In children below 2 years of age, a medical advice is recommended. The rehydration dose and its route of administration (oral-IV) should be adapted to the severity of the diarrhoea and to the age and state of health of the patient.

Pregnancy: Monitoring of pregnancies exposed to this medicines insufficient to rule out any risk. As a precautionary measure, it is preferable to weigh the benefits/risks before using this medicine during pregnancy.

Breast-Feeding: It is not absorbed. In the absence of data, it is preferable to weight benefit/risk before using it during lactation.

Undesirable Effects: (Side effects)

Rare: Flatulence.
Unknown frequency: Constipation, serious blood infection (sepsis in critically ill or immunocompromised patients).
Very rare: Allergic reactions: pruritus, wheal formation (urticaria), skin rash, either locally restricted or affecting the entire body (local or generalised exanthema), swelling of the connective tissue of the face (angioedema). Anaphylactic reaction or even shock. Fungemia in patients with a central venous catheter, in hospitalised, and immunocompromised patients.

Overdosage: Saccharomyces boulardii is not absorbed; there is no reason to expect an overdose.

Instructions: Keep all medicines out of the reach of children. Protect from light, heat and moisture. Store below 30°C. Product contains lactose. To be sold on the prescription of a registered medical practitioner only.

Manufacturer & Buy Online:

Enflor is manufactured by: Biocodex.

This is the link to its manufacturer: https://www.biocodex.com

It is marketed by: Martin Dow Pharmaceuticals (Pvt) Ltd.

This is the link to its marketed company: https://martindow.com

To buy online, go to the: https://dvago.pk