Azipos

Azipos (azithromycin) Capsule is a nitrogen-containing macrolide (azalide). It is generally used for the treatment of a variety of infections. Its antimicrobial activity azithromycin has been shown to be active against most isolates of the following microorganisms: gram-positive bacteria, gram-negative bacteria, and other bacteria & anaerobic bacteria.

Package contains: Azipos contains 10 Capsules of 250mg. It is also available in 500mg capsules.

Composition:

Each capsule contains:

Azithromycin as dihydrate U.S.P 250mg.

Product Specfications: USP Specs.

Dosage & Administration: To be sold on the prescription of a registered medical practitioner only. For details, see the enclosed leaflet. The dosage of AZIPOS (Azithromycin)

In acute bacterial exacerbations of chronic bronchitis: 500 mg once daily for 3 days or 500 mg as a single dose on day 1, followed by 250 mg once daily on days 2 through 5.
In otitis media: 500mg once daily for 3 days; Alternatively initially 500 mg once daily for 1 day, then 250mg once daily for 4 days.
In uncomplicated skin and skin structure infections: 500 mg as a single dose on day 1, followed by 250 mg once daily on days 2 through 5.
In mild to moderate typhoid due to multiple antibacterial resistant organisms: Adult Dose: 500 mg once daily for 7 days. Child 6 months and over: 10mg/kg (to a maximum of 500 mg) once daily for 7 days.
In community-acquired pneumonia, low to moderate severity: 500 mg once daily for 3 days; alternatively, initially 500 mg once daily for 1 day, then 250mg once daily for 4 days.
In community-acquired pneumonia, high severity: Initially 500 mg once daily intravenously for at least 2 days, then 500mg once daily for a total duration of 7-10 days.
In antibacterial prophylaxis for insertion of intrauterine device: one single 1000 mg dose.
In prevention of secondary case of invasive group A streptococcal infection in patients who are allergic to penicillin: Child 6 months to 11 years: 12mg/kg once daily (maximum per dose 500mg) for 5 days. Child 12-17 years & Adult: 500 mg once daily for 5 days.
In uncomplicated Gonorrhea: one single 1000 mg dose.
In urethritis and cervicitis: one single 1000 mg dose.
In genital ulcer disease in men (chancroid): one single 1000 mg dose.
The capsule formulation should be given at least 1 hour before and 2 hours after a meal.

Indications & Usage: Uses of Azipos medicine for adult Patients:

Acute bacterial exacerbations of chronic bronchitis.
Otitis media, Pharyngitis & tonsillitis.
Uncomplicated skin and skin structure infections.
Mild to moderate typhoid due to multiple antibacterial resistant organisms.
Community-acquired pneumonia, low to moderate severity.
Community-acquired pneumonia, high severity.
Antibacterial prophylaxis for insertion of intrauterine device.
Prevention of secondary cases of invasive group A streptococcal infection in patients who are allergic to penicillin.
Uncomplicated Gonorrhoea.
Urethritis and cervicitis due to Chlamydia trachomatis or Neisseria gonorrhoea.
Genital ulcer disease in men due to Haemophilus ducreyi (chancroid).

Contraindications: It is contraindicated:

In patients with known hypersensitivity to azithromycin, erythromycin, any macrolide or ketolide drug.
in patients with a history of cholestatic jaundice/hepatic dysfunction associated with prior use of azithromycin.

Adverse Reactions: The reported adverse events of azithromycin are; angioedema, cholestatic jaundice, nausea, vomiting, diarrhoea, or abdominal pain, palpitations, chest pain, dyspepsia, flatulence, melena, oral moniliasis, vaginitis, nephritis, dizziness, headache, vertigo, somnolence, fatigue, rash, pruritus, photosensitivity, angioedema, acute otitis media, headache, constipation, anorexia, enteritis, gastritis, anemia, leukopenia, hyperkinesia, agitation, nervousness, insomnia, face edema, fungal infection, malaise, pain, allergic reaction, cough, pharyngitis, pleural effusion, rhinitis, eczema, fungal dermatitis, sweating, urticaria, vesiculobullous rash and conjunctivitis.

The additional report adverse events of azithromycin are; arthralgia, edema, arrhythmias including ventricular tachycardia and hypotension, QT prolongation and torsades de pointes, pseudomembranous colitis, pancreatitis, oral candidiasis, pyloric stenosis, tongue discoloration, asthenia, paresthesia, anaphylaxis, interstitial nephritis, acute renal failure, vaginitis, thrombocytopenia, abnormal liver function, hepatic necrosis, hepatic failure, convulsions, vertigo, syncope, aggressive reaction, anxiety, serious skin reactions etc.

Pregnancy & Lactation: Available data from published observational studies, case series, and case reports over several decades do not suggest an increased risk for major birth defects, miscarriage, or adverse maternal or fetal outcomes with azithromycin use in pregnant women.

Azithromycin is present in human milk. There are no available data on the effects of azithromycin on milk production. The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for azithromycin and any potential adverse effects on the breastfed infant from azithromycin or from the underlying maternal condition.

Instructions: Keep out of the reach of children. Store below 30° C in a dry place. Protect from sunlight. Detailed prescribing information is available at the manufacturer’s website.

Manufacturer & Buy Online:

Azipos is manufactured By: Titlis Pharma Pvt Ltd: http://www.titlispharma

It is marketed By: Highnoon Laboratories Ltd: https://highnoon

You can purchase it online at this link: https://nexthealth.pk