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Cef-Od

Cef-Od (Cefixime) 400 mg by CCL Pharmaceuticals is a third-generation oral cephalosporin antibiotic supplied as 5 Capsules. It is mainly used for bacterial infections.

Package Contains: Each Cef-Od Capsule package contains 5 capsules of 400 mg & a leaflet. It is also available in 200 mg tablet form. Cef-Od

Composition:

Each capsule contains:

Cefixime trihydrate USP equivalent to Cefixime 400 mg.

( CCL Pharmaceuticals Specifications )

Dosage: One capsule daily or as directed by the Physician.

Uses / Indications:

  • Uncomplicated urinary tract infections: Cef-Od is indicated for the treatment of adults and pediatric patients six months of age or older with uncomplicated urinary tract infections caused by susceptible isolates of Escherichia coli and Proteus mirabilis.
  • Otitis media: Cef-Od is indicated for the treatment of adults and pediatric patients six months of age or older with otitis media caused by susceptible isolates of Haemophilus influenzae, moraxilla catarrhalis, and streptococcus pyogenes.
  • Pharyngitis and tonsillitis: Cef-Od is indicated in the treatment of adults and pediatric patients six months of age or older with pharyngitis and tonsillitis caused by susceptible isolates of streptococcus pyogenes.
  • Acute Exacerbations of chronic bronchitis: Cef-Od is indicated in the treatment of adults and pediatric patients six months of age or older with acute exacerbations of chronic bronchitis caused by susceptible isolates of streptococcus pneumoniae and homophilous influenza.
  • Uncomplicated Gonorrhea ( cervical / urethral ): Cef-Od is indicated in the treatment of adults and pediatric patients six months of age or older with uncomplicated Gonorrhea ( cervical / urethral ) caused by susceptible isolates of nesseria and gonorrhea ( penicillinase-and-non-pencillinase-producing isolates ).

Dosage & Administration:

  • Adults: The recommended dose of Cefixime is 400 mg. This may be given as a 400 mg capsule daily or the 200 mg tablet given every 12 hours. For the treatment of uncomplicated cervical/urethral gonococcal infections, a single oral dose of 400 mg is recommended.
  • Pediatric patients: The recommended dose is 8 mg/kg/day of the suspension. This may be administered as a single dose or may be given in two divided doses, as 4 mg/kg every 12 hours.

Side Effects / Adverse Reactions: The most commonly seen adverse reactions noted were gastrointestinal events, which were reported in 30% of adult patients on either the twice-daily or the once-daily regimen.

  • Individual adverse reactions included;
  • Diarrhea 16%
  • Frequent stool 6%
  • Abdominal pain 3%
  • Nausea 7%
  • Dyspepsia 3%
  • Flatulence 4%
  • Other adverse reactions: Genital pruritus, vaginitis, Candidiasis, toxic epidermal necrolysis.

Warnings / Precautions:

  • Hypersensitivity Reactions: Anaphylactic / anaphylactions have been reported with the use of Cefixime. Before therapy with Cef-Od is instituted, careful inquiry should be made to determine whether the patient has had previous Hypersensitivity reactions to Cephalosporins, penicillins, or other drugs. If this product is to be given to penicillin-sensitive patients, caution should be exercised because cross-hypersensitivity among beta-lactam antibacterial drugs has been clearly documented and may occur in up to 10% of patients with a history of penicillin If an allergic reaction to Cef-Od occurs, discontinue the drug.
  • Clostridium difficile-Associated Diarrhea: CDAD may range in severity from child diarrhea to fetal. Treatment with antibacterial agents alters the normal flora of the colon, leading to overgrowth of C difficile.
  • Dose Adjustment in Renal Impairment: The dose of Cef-Od should be adjusted in patients with renal Impairment as well as those undergoing continuous ambulatory peritoneal dialysis and hemodialysis. Patients on dialysis should be monitored carefully.
  • Coagulation Effects: Cephalosporins including Cef-Od may be associated with a fall in prothrombin activity. Prothrombin time should be monitored in patients at risk, and exogenous vitamin K administered as indicated.

Use In Pregnancy: This drug should be used during pregnancy only if clearly needed.

Overdose: Gastric lavage may be indicated; otherwise, no specific antidote exists. Cefixime is not removed in significant quantities from the circulation by hemodialysis or peritoneal dialysis.

Contraindications: Cef-Od (Cefixime) is contraindicated in patients with known allergy to Cefixime or other Cephalosporins.

Instructions:

Store below 30°C.

Protect from heat, sunlight & moisture. Keep out of the reach of children.

To be sold on the prescription of a registered medical practitioner only.

Note: For detailed information, see package insert.

Manufacturer & Buy Online:

Cef-Od tablets are manufactured by: Pharmacol (Pvt.) Ltd.

This is the link to the manufacturer: https://pharmapedia.pro

It is manufactured for: CCL Pharmaceuticals (Pvt.) Ltd.

This is the link to the manufacturer for the company: https://cclpharma

You can buy it online at: https://dwatson.pk

Or you can purchase it from any nearby pharmacy. It is currently (2026) available at the retail price of around 560 rupees.

 

By: Munee

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