Xifarox

Xifarox (Cefadroxil) by Getz Pharma is a 125 mg/5 mL strength powder for suspension, available in a 60 mL pack in pineapple flavour. Cefadroxil is a cephalosporin for oral administration, which inhibits bacterial wall synthesis of actively dividing cells by binding to one or more penicillin-binding proteins. The result is the formation of a defective cell wall that is osmotically unstable and bacterial cell lysis.

Package Contains: Each Xifarox package contains a 60ml (after reconstitution) suspension bottle, 125 mg/5 mL strength & a leaflet. It is also available in the form of capsules and drops.

Composition:

Each reconstituted 5mL contains:

Cefadroxil monohydrate equivalent to

Cefadroxil USP 125mg

Dosage: As directed by the physician or see package insert for full prescribing information.

Directions for preparation: Tap bottle to loosen powder. Add previously boiled and cooled water up to the mark on the bottle and shake well. Add additional water, if required, upto the mark on the bottle and shake well. After reconstitution, the suspension can be stored in a refrigerator (2°C – 8°C) and used within 14 days. For accurate measurement of dosage, a spoon is provided. Shake well before use.

Indications / Uses: Xifarox suspension is indicated for the treatment of the following infections caused by cefadroxil-susceptible organisms, when an oral therapy is indicated:

Streptococcal pharyngitis and tonsillitis
Bronchopneumonia, bacterial pneumonia
Urinary tract infections: pyelonephritis, cystitis
Skin and soft tissue infections: abscesses, furunculosis, impetigo, erysipelas, pyoderma, lymphadenitis
Other infections: Osteomyelitis and septic arthritis

To reduce the development of drug-resistant bacteria and maintain the effectiveness of cefadroxil and other antibacterial drugs, cefadroxil should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.

Dosage & Administration:

Adults: The dosage depends on the susceptibility of the pathogens, the severity of the disease and on the clinical status of the patient (renal and hepatic function).
Skin and Skin Structure Infections: For skin and skin structure infections, the usual dosage is 1g per day in single or divided doses.
Pharyngitis and Tonsillitis: For treatment of group A beta-hemolytic streptococcal pharyngitis and tonsillitis, the usual dose is 1g per day in single or two equally divided doses for 10 days.
Urinary Tract Infections: For uncomplicated urinary tract infections (i.e., cystitis) the usual dosage is 1g or 2g per day in single or divided doses. For all other urinary tract infections, the usual dosage is 2g per day in divided doses.
Upper and lower respiratory tract infections: For mild infections, the usual dosage is 1g per day in two equally divided doses. For moderate to severe infections, the recommended dosage is 1g to 2g in two equally divided doses.
Children: The recommended dosage for children is 25-50mg/kg/day in two equally divided doses (every 12 hours) as indicated. For pharyngitis, tonsillitis and impetigo, the recommended daily dosage may be administered as a single dose or in two equally divided doses (every 12 hours).

Contraindications: Cefadroxil is contraindicated in patients with:

Hypersensitivity to cefadroxil, to any of the cephalosporins or to any of the excipients of the product.
History of severe reactions to penicillins or to any other beta-lactam drugs.

Side Effects: Common: Nausea, vomiting, diarrhoea, dyspepsia, abdominal pain, glossitis, pruritus, rash, allergic exanthema and urticaria.
Uncommon: Clinical pictures due to a growth of opportunistic organisms (fungi) such as vaginal mycoses, thrush.
Rare: Eosinophilia, thrombocytopenia, leucopenia, neutropenia, agranulocytosis; rare cases during prolonged use, which subside upon discontinuation of therapy; serum sickness-like reactions, cholestasis and idiosyncratic hepatic failure have been reported, minor elevation of serum transaminases (ASAT, ALAT) and alkaline phosphatases, angioneurotic edema, arthralgia, interstitial nephritis and drug fever.
Very rare: Haemolytic anemia of immunologic origin, immediate allergic reaction (anaphylactic shock), headache, sleeplessness, dizziness, nervousness, pseudomembranous colitis has been reported (may range in severity from mild to life-threatening), Stevens-Johnson syndrome and erythema multiforme have been reported, fatigue, direct and indirect positive Coombs’ tests.

Instruction:

Do not store above 30°C.
Protect from sunlight and moisture.
Keep out of reach of children.
Keep the cap tightly closed after use.
To be sold on prescription of a Registered medical practitioner only.

Manufacturer & Buy Online:

Xifarox suspension is manufactured by: Getz Pharma (PVT) Limited.

This is the link to the manufacturer: https://getzpharma

You can buy it online at: https://tabletpharmacy.com.pk

Or you can purchase it from any nearby pharmacy. It is currently (2026) available at the retail price of around 183 rupees.

By: Gul.