Terbisil spray

Terbisil spray (Terbinafine Hydrochloride B.P 1%) (J.P Specs) 30ml belongs to the Pharmacotherapeutic group & it is an antifungal spray for topical use.

Package Contains: Each box of Terbisil contains a plastic spray bottle of 30ml.

Composition: Each gram contains:

Terbinafine hydrochloride B.P. 10mg

Product Complies with J.P. specs.

Dosage & Application: Clean and dry the affected area. Press actuator to spray over affected area.

Indication: Terbisil spray is indicated in the treatment of fungal infections of the skin caused by dermatophytes. It is also indicated in the treatment of pityriasis versicolor due to Malassezia furfur. Topical terbisil spray is not effective in onychomycosis.

Terbinafine is an allylamine which has a broad spectrum of antifungal activity in fungal infections of the skin caused by dermatophytes such as Trichophyton (e.g., T. rubrum, T. mentagrophytes, T. verrucosum, T. violaceum), Microsporum canis, and Epidermophyton floccosum. At low concentrations, Terbinafine is fungicidal against dermatophytes and moulds. The activity against yeasts is fungicidal (e.g. Pityrosporum orbiculare or Malassezia furfur) or fungistatic, depending on the species.

Terbinafine interferes specifically with fungal sterol biosynthesis at an early step. This leads to a deficiency in ergosterol and to an intracellular accumulation of squalene, resulting in fungal cell death. Terbinafine does not influence the metabolism of hormones or other drugs.

Dosage & Administration: Not to be used in children under 16 years of age. Adults: It is applied once daily or twice daily, for one week, depending on the indication.

Duration and frequency of treatment:

Indication	Duration of Treatment
Tinea Pedis	1 Week, once a day
Tinea Corporis/Cruris	1 Week, once a day
Pityriasis Versicolor	1 Week, twice a day.

Relief of clinical symptoms usually occurs within a few days. Irregular use or premature discontinuation of treatment carries the risk of recurrence. If there are no signs of improvement after one week, a physician should be consulted.

Clean and dry the affected areas thoroughly before applying Terbisil spray. Press actuator to spray over affected area. A sufficient amount of spray solution should be applied to wet the treatment area(s) thoroughly, and to cover the affected skin and the surrounding area.

Contraindications: Known hypersensitivity to Terbinafine or any of the excipients contained in the spray solution.

Special Warnings & Precautions For Use: Terbisil spray should be used with caution in patients with lesions where alcohol could be irritating.

The spray is for external use only. It may be irritating to the eyes. Terbisil spray should not be used on the face.
In case of accidental contact with the eyes, rinse eyes thoroughly with running water.
Avoid inhalation. In case of accidental inhalation, consult a physician if any symptoms develop or persist. Terbisil spray contains propylene glycol, which may cause skin irritation.
As a precaution, it is recommended that other medicinal products should not be applied to the treated areas.

Pregnancy & Lactation: Animal studies did not reveal any teratogenic or embryofetotoxic potential of Terbinafine. It should not be used during pregnancy unless clearly necessary.

Terbinafine is excreted in breast milk. Therefore, nursing mothers should not receive the spray while breastfeeding. Infants must not be allowed to come into contact with any treated skin, including the breast.

Undesirable Effects / Side Effects: Local symptoms such as pruritus, skin exfoliation, application site pain, application site irritation, pigmentation disorder, skin burning sensation, erythema and scab may occur at the site of application.

These minor symptoms must be distinguished from hypersensitivity reactions such as widespread pruritus, rash, bullous eruptions and hives, which are reported in sporadic cases and require discontinuation. In rare cases, the underlying fungal infection may be aggravated.

Skin & Subcutaneous Tissue Disorders:

Common: Skin exfoliation, pruritus.
Uncommon: Skin lesion, scab, skin disorder, pigmentation disorder, erythema, skin burning sensation.
Rare: Dry skin, contact dermatitis, eczema.

Instructions: Store between 15°C to 30°C. Protect from light, heat & freezing. Keep the container tightly closed. Keep out of the reach of children. To be sold on the prescription of a registered medical practitioner only. For further information, see enclosed leaf insert. It is for external use only.

Manufacturer & Buy Online:

Terbisil spray is manufactured by: Saffron Pharmaceuticals (Pvt.) Ltd.

This is the link to the manufacturer: https://www.saffronpharma

You can purchase it online from: https://www.dvago.pk